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Outer Hair Cell Lateral Wall Structure Constrains the Mobility of Plasma Membrane Proteins

Nature’s fastest motors are the cochlear outer hair cells (OHCs). These sensory cells use a membrane protein, Slc26a5 (prestin), to generate mechanical force at high frequencies, which is essential for explaining the exquisite hearing sensitivity of mammalian ears. Previous studies suggest that Slc2...

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Detalles Bibliográficos
Autores principales: Yamashita, Tetsuji, Hakizimana, Pierre, Wu, Siva, Hassan, Ahmed, Jacob, Stefan, Temirov, Jamshid, Fang, Jie, Mellado-Lagarde, Marcia, Gursky, Richard, Horner, Linda, Leibiger, Barbara, Leijon, Sara, Centonze, Victoria E., Berggren, Per-Olof, Frase, Sharon, Auer, Manfred, Brownell, William E., Fridberger, Anders, Zuo, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564264/
https://www.ncbi.nlm.nih.gov/pubmed/26352669
http://dx.doi.org/10.1371/journal.pgen.1005500