High-throughput determination of RNA structure by proximity ligation

We present an unbiased method to globally resolve RNA structures through pairwise contact measurements between interacting regions. RNA Proximity Ligation (RPL) uses proximity ligation of native RNA followed by deep sequencing to yield chimeric reads with ligation junctions in the vicinity of struct...

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Detalles Bibliográficos
Autores principales: Ramani, Vijay, Qiu, Ruolan, Shendure, Jay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564351/
https://www.ncbi.nlm.nih.gov/pubmed/26237516
http://dx.doi.org/10.1038/nbt.3289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564351/
https://www.ncbi.nlm.nih.gov/pubmed/26237516
http://dx.doi.org/10.1038/nbt.3289

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