Expression of miR-200c in claudin-low breast cancer alters stem cell functionality, enhances chemosensitivity and reduces metastatic potential

Claudin-low tumors are a highly aggressive breast cancer subtype with no targeted treatments and a clinically documented resistance to chemotherapy. They are significantly enriched in cancer stem cells (CSCs), which makes claudin-low tumor models particularly attractive for studying CSC behavior and...

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Detalles Bibliográficos
Autores principales: Knezevic, Jana, Pfefferle, Adam D., Petrovic, Ivana, Greene, Stephanie B., Perou, Charles M., Rosen, Jeffrey M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564359/
https://www.ncbi.nlm.nih.gov/pubmed/25746005
http://dx.doi.org/10.1038/onc.2015.48

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564359/
https://www.ncbi.nlm.nih.gov/pubmed/25746005
http://dx.doi.org/10.1038/onc.2015.48

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