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Oral and inhaled p38 MAPK inhibitors: effects on inhaled LPS challenge in healthy subjects
BACKGROUND: Inhaled LPS causes neutrophilic airway inflammation in healthy subjects. We compared the effects of p38 MAPK inhibitors and fluticasone propionate on the LPS response. METHODS: Three randomised, double-blind, placebo-controlled, single dose crossover studies were performed. Active treatm...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564450/ https://www.ncbi.nlm.nih.gov/pubmed/26265232 http://dx.doi.org/10.1007/s00228-015-1920-1 |