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Characterization of a Bivalent Vaccine Capable of Inducing Protection Against Both Ebola and Cross-clade H5N1 Influenza in Mice

Background. Ebola virus (EBOV) is a lethal pathogen that causes up to 90% mortality in humans, whereas H5N1 avian influenza has a 60% fatality rate. Both viruses are considered pandemic threats. The objective was to evaluate the protective efficacy of a bivalent, recombinant vesicular stomatitis vir...

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Detalles Bibliográficos
Autores principales: Wong, Gary, Qiu, Xiangguo, Ebihara, Hideki, Feldmann, Heinz, Kobinger, Gary P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Infectious Diseases Society of America 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564552/
https://www.ncbi.nlm.nih.gov/pubmed/26022441
http://dx.doi.org/10.1093/infdis/jiv257