Morphine Reduces Myocardial Infarct Size via Heat Shock Protein 90 in Rodents

Opioids reduce injury from myocardial ischemia-reperfusion in humans. In experimental models, this mechanism involves GSK3β inhibition. HSP90 regulates mitochondrial protein import, with GSK3β inhibition increasing HSP90 mitochondrial content. Therefore, we determined whether morphine-induced cardio...

Descripción completa

Detalles Bibliográficos
Autores principales: Small, Bryce A., Lu, Yao, Hsu, Anna K., Gross, Garrett J., Gross, Eric R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564588/
https://www.ncbi.nlm.nih.gov/pubmed/26413502
http://dx.doi.org/10.1155/2015/129612

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564588/
https://www.ncbi.nlm.nih.gov/pubmed/26413502
http://dx.doi.org/10.1155/2015/129612

Ejemplares similares