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Morphine Reduces Myocardial Infarct Size via Heat Shock Protein 90 in Rodents

Opioids reduce injury from myocardial ischemia-reperfusion in humans. In experimental models, this mechanism involves GSK3β inhibition. HSP90 regulates mitochondrial protein import, with GSK3β inhibition increasing HSP90 mitochondrial content. Therefore, we determined whether morphine-induced cardio...

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Detalles Bibliográficos
Autores principales:	Small, Bryce A., Lu, Yao, Hsu, Anna K., Gross, Garrett J., Gross, Eric R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564588/ https://www.ncbi.nlm.nih.gov/pubmed/26413502 http://dx.doi.org/10.1155/2015/129612

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