PE and PS Lipids Synergistically Enhance Membrane Poration by a Peptide with Anticancer Properties

Polybia-MP1 (MP1) is a bioactive host-defense peptide with known anticancer properties. Its activity is attributed to excess serine (phosphatidylserine (PS)) on the outer leaflet of cancer cells. Recently, higher quantities of phosphatidylethanolamine (PE) were also found at these cells’ surface. We...

Descripción completa

Detalles Bibliográficos
Autores principales: Leite, Natália Bueno, Aufderhorst-Roberts, Anders, Palma, Mario Sergio, Connell, Simon D., Neto, João Ruggiero, Beales, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2015
Materias:
Membranes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564682/
https://www.ncbi.nlm.nih.gov/pubmed/26331251
http://dx.doi.org/10.1016/j.bpj.2015.07.033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564682/
https://www.ncbi.nlm.nih.gov/pubmed/26331251
http://dx.doi.org/10.1016/j.bpj.2015.07.033

Ejemplares similares