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Direct label-free measurement of the distribution of small molecular weight compound inside thick biological tissue using coherent Raman microspectroscopy

Distributions of small molecular weight (less than 300 Da) compounds inside biological tissue have been obscure because of the lack of appropriate methods to measure them. Although fluorescence techniques are widely used to characterise the localisation of large biomolecules, they cannot be easily a...

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Detalles Bibliográficos
Autores principales: Kawagishi, Masahiko, Obara, Yuki, Suzuki, Takayuki, Hayashi, Masumi, Misawa, Kazuhiko, Terada, Sumio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564726/
https://www.ncbi.nlm.nih.gov/pubmed/26353981
http://dx.doi.org/10.1038/srep13868