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Direct label-free measurement of the distribution of small molecular weight compound inside thick biological tissue using coherent Raman microspectroscopy
Distributions of small molecular weight (less than 300 Da) compounds inside biological tissue have been obscure because of the lack of appropriate methods to measure them. Although fluorescence techniques are widely used to characterise the localisation of large biomolecules, they cannot be easily a...
Autores principales: | Kawagishi, Masahiko, Obara, Yuki, Suzuki, Takayuki, Hayashi, Masumi, Misawa, Kazuhiko, Terada, Sumio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564726/ https://www.ncbi.nlm.nih.gov/pubmed/26353981 http://dx.doi.org/10.1038/srep13868 |
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