Generation of gene-modified goats targeting MSTN and FGF5 via zygote injection of CRISPR/Cas9 system

Recent advances in the study of the CRISPR/Cas9 system have provided a precise and versatile approach for genome editing in various species. However, the applicability and efficiency of this method in large animal models, such as the goat, have not been extensively studied. Here, by co-injection of...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Xiaolong, Yu, Honghao, Lei, Anmin, Zhou, Jiankui, Zeng, Wenxian, Zhu, Haijing, Dong, Zhiming, Niu, Yiyuan, Shi, Bingbo, Cai, Bei, Liu, Jinwang, Huang, Shuai, Yan, Hailong, Zhao, Xiaoe, Zhou, Guangxian, He, Xiaoling, Chen, Xiaoxu, Yang, Yuxin, Jiang, Yu, Shi, Lei, Tian, Xiue, Wang, Yongjun, Ma, Baohua, Huang, Xingxu, Qu, Lei, Chen, Yulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564737/
https://www.ncbi.nlm.nih.gov/pubmed/26354037
http://dx.doi.org/10.1038/srep13878

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564737/
https://www.ncbi.nlm.nih.gov/pubmed/26354037
http://dx.doi.org/10.1038/srep13878

Ejemplares similares