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Characterization of exogenous DNA mobility in live cells through fluctuation correlation spectroscopy

The spatial-temporal dynamics of delivered DNA is a critical aspect influencing successful gene delivery. A comprehensive model of DNA lipoplex trafficking through live cells has yet to be demonstrated. Here the bioimaging approaches Raster Image Correlation Spectroscopy (RICS) and image-Means Squar...

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Detalles Bibliográficos
Autores principales: Mieruszynski, Stephen, Digman, Michelle A., Gratton, Enrico, Jones, Mark R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564760/
https://www.ncbi.nlm.nih.gov/pubmed/26354725
http://dx.doi.org/10.1038/srep13848