Proton beam radiation induces DNA damage and cell apoptosis in glioma stem cells through reactive oxygen species

Glioblastoma multiforme (GBM) is among the most lethal of human malignancies. Most GBM tumors are refractory to cytotoxic therapies. Glioma stem cells (GSCs) significantly contribute to GBM progression and post-treatment tumor relapse, therefore serving as a key therapeutic target; however, GSCs are...

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Detalles Bibliográficos
Autores principales: Alan Mitteer, R., Wang, Yanling, Shah, Jennifer, Gordon, Sherika, Fager, Marcus, Butter, Param-Puneet, Jun Kim, Hyun, Guardiola-Salmeron, Consuelo, Carabe-Fernandez, Alejandro, Fan, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564801/
https://www.ncbi.nlm.nih.gov/pubmed/26354413
http://dx.doi.org/10.1038/srep13961

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564801/
https://www.ncbi.nlm.nih.gov/pubmed/26354413
http://dx.doi.org/10.1038/srep13961

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