Structural Dynamics and Thermostabilization of Neurotensin Receptor 1

[Image: see text] The neurotensin receptor NTSR1 binds the peptide agonist neurotensin (NTS) and signals preferentially via the G(q) protein. Recently, Grisshammer and co-workers reported the crystal structure of a thermostable mutant NTSR1-GW5 with NTS bound. Understanding how the mutations thermos...

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Detalles Bibliográficos
Autores principales: Lee, Sangbae, Bhattacharya, Supriyo, Tate, Christopher G., Grisshammer, Reinhard, Vaidehi, Nagarajan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564841/
https://www.ncbi.nlm.nih.gov/pubmed/25807267
http://dx.doi.org/10.1021/jp510735f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564841/
https://www.ncbi.nlm.nih.gov/pubmed/25807267
http://dx.doi.org/10.1021/jp510735f

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