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Rhein antagonizes P2X(7) receptor in rat peritoneal macrophages

P2X(7) receptor plays important roles in inflammation and immunity, and thereby it serves as a potential therapeutic target for inflammatory diseases. Rhein, an anthraquinone derivative, exhibits significant anti-inflammatory and immunosuppressive activities in therapy. However, the underlying mecha...

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Detalles Bibliográficos
Autores principales: Hu, Fen, Xing, Fulin, Zhu, Ge, Xu, Guangxue, Li, Cunbo, Qu, Junle, Lee, Imshik, Pan, Leiting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564849/
https://www.ncbi.nlm.nih.gov/pubmed/26354875
http://dx.doi.org/10.1038/srep14012