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Rhein antagonizes P2X(7) receptor in rat peritoneal macrophages
P2X(7) receptor plays important roles in inflammation and immunity, and thereby it serves as a potential therapeutic target for inflammatory diseases. Rhein, an anthraquinone derivative, exhibits significant anti-inflammatory and immunosuppressive activities in therapy. However, the underlying mecha...
Autores principales: | Hu, Fen, Xing, Fulin, Zhu, Ge, Xu, Guangxue, Li, Cunbo, Qu, Junle, Lee, Imshik, Pan, Leiting |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564849/ https://www.ncbi.nlm.nih.gov/pubmed/26354875 http://dx.doi.org/10.1038/srep14012 |
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