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Loss of G2 subunit of vacuolar-type proton transporting ATPase leads to G1 subunit upregulation in the brain
Vacuolar-type ATPase (V-ATPase) is a primary proton pump with versatile functions in various tissues. In nerve cells, V-ATPase is required for accumulation of neurotransmitters into secretory vesicles and subsequent release at the synapse. Neurons express a specific isoform (G2) of the G subunit of...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564858/ https://www.ncbi.nlm.nih.gov/pubmed/26353914 http://dx.doi.org/10.1038/srep14027 |