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Loss of G2 subunit of vacuolar-type proton transporting ATPase leads to G1 subunit upregulation in the brain

Vacuolar-type ATPase (V-ATPase) is a primary proton pump with versatile functions in various tissues. In nerve cells, V-ATPase is required for accumulation of neurotransmitters into secretory vesicles and subsequent release at the synapse. Neurons express a specific isoform (G2) of the G subunit of...

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Detalles Bibliográficos
Autores principales: Kawamura, Nobuyuki, Sun-Wada, Ge-Hong, Wada, Yoh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564858/
https://www.ncbi.nlm.nih.gov/pubmed/26353914
http://dx.doi.org/10.1038/srep14027

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