InbR, a TetR family regulator, binds with isoniazid and influences multidrug resistance in Mycobacterium bovis BCG

Isoniazid (INH), an anti-tuberculosis (TB) drug, has been widely used for nearly 60 years. However, the pathway through which Mycobacterium tuberculosis responds INH remain largely unclear. In this study, we characterized a novel transcriptional factor, InbR, which is encoded by Rv0275c and belongs...

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Detalles Bibliográficos
Autores principales: Yang, Min, Gao, Chun-Hui, Hu, Jialing, Zhao, Lei, Huang, Qiaoyun, He, Zheng-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564863/
https://www.ncbi.nlm.nih.gov/pubmed/26353937
http://dx.doi.org/10.1038/srep13969

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564863/
https://www.ncbi.nlm.nih.gov/pubmed/26353937
http://dx.doi.org/10.1038/srep13969

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