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InbR, a TetR family regulator, binds with isoniazid and influences multidrug resistance in Mycobacterium bovis BCG
Isoniazid (INH), an anti-tuberculosis (TB) drug, has been widely used for nearly 60 years. However, the pathway through which Mycobacterium tuberculosis responds INH remain largely unclear. In this study, we characterized a novel transcriptional factor, InbR, which is encoded by Rv0275c and belongs...
Autores principales: | Yang, Min, Gao, Chun-Hui, Hu, Jialing, Zhao, Lei, Huang, Qiaoyun, He, Zheng-Guo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564863/ https://www.ncbi.nlm.nih.gov/pubmed/26353937 http://dx.doi.org/10.1038/srep13969 |
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