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The Complex Energy Landscape of the Protein IscU

IscU, the scaffold protein for iron-sulfur (Fe-S) cluster biosynthesis in Escherichia coli, traverses a complex energy landscape during Fe-S cluster synthesis and transfer. Our previous studies showed that IscU populates two interconverting conformational states: one structured (S) and one largely d...

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Detalles Bibliográficos
Autores principales: Bothe, Jameson R., Tonelli, Marco, Ali, Ibrahim K., Dai, Ziqi, Frederick, Ronnie O., Westler, William M., Markley, John L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564936/
https://www.ncbi.nlm.nih.gov/pubmed/26331259
http://dx.doi.org/10.1016/j.bpj.2015.07.045