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Study protocol of the TRICOLORE trial: a randomized phase III study of oxaliplatin-based chemotherapy versus combination chemotherapy with S-1, irinotecan, and bevacizumab as first-line therapy for metastatic colorectal cancer

BACKGROUND: Metastatic colorectal cancer carries a poor prognosis and cannot be cured by currently available therapy. Chemotherapy designed to prolong survival and improve the quality of life (QOL) of patients is the mainstay of treatment. Standard regimens of FOLFOX/bevacizumab and CapeOX/bevacizum...

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Detalles Bibliográficos
Autores principales: Komatsu, Yoshito, Ishioka, Chikashi, Shimada, Ken, Yamada, Yasuhide, Gamoh, Makio, Sato, Atsushi, Yamaguchi, Tatsuro, Yuki, Satoshi, Morita, Satoshi, Takahashi, Shin, Goto, Rei, Kurihara, Minoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565014/
https://www.ncbi.nlm.nih.gov/pubmed/26353772
http://dx.doi.org/10.1186/s12885-015-1630-1