Cargando…
Kinetic Detection of Orthogonal Protein and Chemical Coordinates in Enzyme Catalysis: Double Mutants of Soybean Lipoxygenase
[Image: see text] Soybean lipoxygenase-1 (SLO-1) is a paradigmatic enzyme system for studying the contribution of hydrogen tunneling to enzymatic proton-coupled electron transfer processes. In this study, the impact of pairs of double mutants on the properties of SLO-1 is presented. Steady-state rat...
Autores principales: | Sharma, Sudhir C., Klinman, Judith P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2015
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565126/ https://www.ncbi.nlm.nih.gov/pubmed/26154975 http://dx.doi.org/10.1021/acs.biochem.5b00374 |
Ejemplares similares
-
Enhanced Rigidification within a Double Mutant of
Soybean Lipoxygenase Provides Experimental Support for Vibronically
Nonadiabatic Proton-Coupled Electron Transfer Models
por: Hu, Shenshen, et al.
Publicado: (2017) -
Dynamically Achieved Active Site Precision in Enzyme
Catalysis
por: Klinman, Judith P.
Publicado: (2014) -
Hydrogen Tunneling in a Prokaryotic Lipoxygenase
por: Carr, Cody A. Marcus, et al.
Publicado: (2014) -
Temporal and spatial resolution of distal protein motions that activate hydrogen tunneling in soybean lipoxygenase
por: Zaragoza, Jan Paulo T., et al.
Publicado: (2023) -
Chemical kinetics and catalysis /
por: Masel, Richard I., 1951-
Publicado: (2001)