Cargando…
Structural Basis of Substrate Recognition by Aldehyde Dehydrogenase 7A1
[Image: see text] Aldehyde dehydrogenase 7A1 (ALDH7A1) is part of lysine catabolism and catalyzes the NAD(+)-dependent oxidation of α-aminoadipate semialdehyde to α-aminoadipate. Herein, we describe a structural study of human ALDH7A1 focused on substrate recognition. Five crystal structures and sma...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2015
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565128/ https://www.ncbi.nlm.nih.gov/pubmed/26260980 http://dx.doi.org/10.1021/acs.biochem.5b00754 |