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Evolution of a Novel Antiviral Immune-Signaling Interaction by Partial-Gene Duplication
The RIG-like receptors (RLRs) are related proteins that identify viral RNA in the cytoplasm and activate cellular immune responses, primarily through direct protein-protein interactions with the signal transducer, IPS1. Although it has been well established that the RLRs, RIG-I and MDA5, activate IP...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565553/ https://www.ncbi.nlm.nih.gov/pubmed/26356745 http://dx.doi.org/10.1371/journal.pone.0137276 |