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Evolution of a Novel Antiviral Immune-Signaling Interaction by Partial-Gene Duplication

The RIG-like receptors (RLRs) are related proteins that identify viral RNA in the cytoplasm and activate cellular immune responses, primarily through direct protein-protein interactions with the signal transducer, IPS1. Although it has been well established that the RLRs, RIG-I and MDA5, activate IP...

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Detalles Bibliográficos
Autores principales: Korithoski, Bryan, Kolaczkowski, Oralia, Mukherjee, Krishanu, Kola, Reema, Earl, Chandra, Kolaczkowski, Bryan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565553/
https://www.ncbi.nlm.nih.gov/pubmed/26356745
http://dx.doi.org/10.1371/journal.pone.0137276