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Inactivated Eyedrop Influenza Vaccine Adjuvanted with Poly(I:C) Is Safe and Effective for Inducing Protective Systemic and Mucosal Immunity

The eye route has been evaluated as an efficient vaccine delivery routes. However, in order to induce sufficient antibody production with inactivated vaccine, testing of the safety and efficacy of the use of inactivated antigen plus adjuvant is needed. Here, we assessed various types of adjuvants in...

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Detalles Bibliográficos
Autores principales: Kim, Eun-Do, Han, Soo Jung, Byun, Young-Ho, Yoon, Sang Chul, Choi, Kyoung Sub, Seong, Baik Lin, Seo, Kyoung Yul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565664/
https://www.ncbi.nlm.nih.gov/pubmed/26355295
http://dx.doi.org/10.1371/journal.pone.0137608