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Can kinomics and proteomics bridge the gap between pediatric cancers and newly designed kinase inhibitors?

The introduction of kinase inhibitors in cancer medicine has transformed chronic myeloid leukemia from a fatal disease into a leukemia subtype with a favorable prognosis by interfering with the constitutively active kinase BCR-ABL. This success story has resulted in the development of multiple kinas...

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Detalles Bibliográficos
Autores principales: van der Sligte, Naomi E., Kampen, Kim R., de Bont, Eveline S. J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Basel 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565869/
https://www.ncbi.nlm.nih.gov/pubmed/26321002
http://dx.doi.org/10.1007/s00018-015-2019-7