Repressed TGF-β signaling through CagA-Smad3 interaction as pathogenic mechanisms of Helicobacter pylori-associated gastritis

Helicobacter pylori (H. pylori) infection causes chronic gastric inflammation, peptic ulceration, and gastric carcinogenesis, in which H. pylori cytotoxin-associated gene A (CagA) plays major pathogenic action. Since transforming growth factor-β (TGF-β) and its signaling also are principally implica...

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Detalles Bibliográficos
Autores principales: Nguyen, Thuy Trang, Kim, Seong-Jin, Park, Jong Min, Hahm, Ki Baik, Lee, Ho-Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566024/
https://www.ncbi.nlm.nih.gov/pubmed/26388668
http://dx.doi.org/10.3164/jcbn.15-38

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566024/
https://www.ncbi.nlm.nih.gov/pubmed/26388668
http://dx.doi.org/10.3164/jcbn.15-38

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