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The splicing regulators Esrp1 and Esrp2 direct an epithelial splicing program essential for mammalian development

Tissue- and cell-type-specific regulators of alternative splicing (AS) are essential components of posttranscriptional gene regulation, necessary for normal cellular function, patterning, and development. Mice with ablation of Epithelial splicing regulatory protein (Esrp1) develop cleft lip and pala...

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Detalles Bibliográficos
Autores principales: Bebee, Thomas W, Park, Juw Won, Sheridan, Katherine I, Warzecha, Claude C, Cieply, Benjamin W, Rohacek, Alex M, Xing, Yi, Carstens, Russ P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566030/
https://www.ncbi.nlm.nih.gov/pubmed/26371508
http://dx.doi.org/10.7554/eLife.08954