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Epigenetic Codes Programing Class Switch Recombination

Class switch recombination imparts B cells with a fitness-associated adaptive ­advantage during a humoral immune response by using a precision-tailored DNA excision and ligation process to swap the default constant region gene of the antibody with a new one that has unique effector functions. This s...

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Detalles Bibliográficos
Autores principales: Vaidyanathan, Bharat, Chaudhuri, Jayanta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566074/
https://www.ncbi.nlm.nih.gov/pubmed/26441954
http://dx.doi.org/10.3389/fimmu.2015.00405