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Epigenetic Codes Programing Class Switch Recombination
Class switch recombination imparts B cells with a fitness-associated adaptive advantage during a humoral immune response by using a precision-tailored DNA excision and ligation process to swap the default constant region gene of the antibody with a new one that has unique effector functions. This s...
Autores principales: | Vaidyanathan, Bharat, Chaudhuri, Jayanta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566074/ https://www.ncbi.nlm.nih.gov/pubmed/26441954 http://dx.doi.org/10.3389/fimmu.2015.00405 |
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