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Novel WT1 Missense Mutations in Han Chinese Women with Premature Ovarian Failure

Premature ovarian failure (POF) is a heterogeneous disease. Though dozens of candidate genes have been identified for the genetic etiology of POF, it is largely unexplained in majority of patients. Recently, Wt1(+/R394W) mice was found to present POF-like phenotype, which indicates that WT1 might be...

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Detalles Bibliográficos
Autores principales: Wang, Huidan, Li, Guangyu, Zhang, Jun, Gao, Fei, Li, Weiping, Qin, Yingying, Chen, Zi-Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566091/
https://www.ncbi.nlm.nih.gov/pubmed/26358501
http://dx.doi.org/10.1038/srep13983