Telomeres are partly shielded from ultraviolet-induced damage and proficient for nucleotide excision repair of photoproducts

Ultraviolet light induces cyclobutane pyrimidine dimers (CPD) and pyrimidine(6–4)pyrimidone photoproducts, which interfere with DNA replication and transcription. Nucleotide excision repair (NER) removes these photoproducts, but whether NER functions at telomeres is unresolved. Here we use immunospo...

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Detalles Bibliográficos
Autores principales: Parikh, Dhvani, Fouquerel, Elise, Murphy, Connor T., Wang, Hong, Opresko, Patricia L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566151/
https://www.ncbi.nlm.nih.gov/pubmed/26351258
http://dx.doi.org/10.1038/ncomms9214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566151/
https://www.ncbi.nlm.nih.gov/pubmed/26351258
http://dx.doi.org/10.1038/ncomms9214

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