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Comparison of circulating lipid profiles between fasting humans and three animal species used in preclinical studies: mice, rats and rabbits

BACKGROUND: Circulating lipid metabolites are associated with many physiological and biological processes in the body, and therefore could be used as biomarkers for evaluating drug efficacy and safety in preclinical studies. However, differences in circulating lipid profiles among humans and animals...

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Detalles Bibliográficos
Autores principales: Ishikawa, Masaki, Saito, Kosuke, Urata, Masayo, Kumagai, Yuji, Maekawa, Keiko, Saito, Yoshiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566205/
https://www.ncbi.nlm.nih.gov/pubmed/26358237
http://dx.doi.org/10.1186/s12944-015-0104-4