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Computer-Assisted Transgenesis of Caenorhabditis elegans for Deep Phenotyping
A major goal in the study of human diseases is to assign functions to genes or genetic variants. The model organism Caenorhabditis elegans provides a powerful tool because homologs of many human genes are identifiable, and large collections of genetic vectors and mutant strains are available. Howeve...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566274/ https://www.ncbi.nlm.nih.gov/pubmed/26163188 http://dx.doi.org/10.1534/genetics.115.179648 |