Development of a robust DNA damage model including persistent telomere-associated damage with application to secondary cancer risk assessment

Mathematical modelling has been instrumental to understand kinetics of radiation-induced DNA damage repair and associated secondary cancer risk. The widely accepted two-lesion kinetic (TLK) model assumes two kinds of double strand breaks, simple and complex ones, with different repair rates. Recentl...

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Detalles Bibliográficos
Autores principales: Rastgou Talemi, Soheil, Kollarovic, Gabriel, Lapytsko, Anastasiya, Schaber, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566481/
https://www.ncbi.nlm.nih.gov/pubmed/26359627
http://dx.doi.org/10.1038/srep13540

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566481/
https://www.ncbi.nlm.nih.gov/pubmed/26359627
http://dx.doi.org/10.1038/srep13540

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