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Effect of Farnesyltransferase Inhibitor R115777 on Mitochondria of Plasmodium falciparum

The parasite Plasmodium falciparum causes severe malaria and is the most dangerous to humans. However, it exhibits resistance to their drugs. Farnesyltransferase has been identified in pathogenic protozoa of the genera Plasmodium and the target of farnesyltransferase includes Ras family. Therefore,...

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Detalles Bibliográficos
Autores principales: Ha, Young Ran, Hwang, Bae-Geun, Hong, Yeonchul, Yang, Hye-Won, Lee, Sang Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Parasitology and Tropical Medicine 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566515/
https://www.ncbi.nlm.nih.gov/pubmed/26323840
http://dx.doi.org/10.3347/kjp.2015.53.4.421