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Blockade of CD82 by a monoclonal antibody potentiates anti-leukemia effects of AraC in vivo
We recently found that CD82 inhibits matrix metalloproteinase 9 and augments adhesion of CD34(+)/CD38(−) acute myelogenous leukemia (AML) cells to the bone marrow (BM) microenvironment. The present study found that the use of an anti-CD82 monoclonal antibody (CD82 mAb) mobilized CD34(+) leukemia cel...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567027/ https://www.ncbi.nlm.nih.gov/pubmed/26139471 http://dx.doi.org/10.1002/cam4.482 |