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Emerging Role of Tyrosine Kinases as Drugable Targets in Cancer

Tyrosine kinases (TKs) play a significant role in cancerogenesis and cancer cell function. Initial developments in this field go back to the early 80s, but the success story really started with the selective BCR-ABL inhibitor, imatinib. Owing to the cancer-driving role of BCR-ABL in chronic myeloid...

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Detalles Bibliográficos
Autores principales: Na, Il-Kang, le Coutre, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567050/
https://www.ncbi.nlm.nih.gov/pubmed/26401097
http://dx.doi.org/10.4137/BMI.S22432