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The Protein Tyrosine Phosphatase Rptpζ Suppresses Osteosarcoma Development in Trp53-Heterozygous Mice

Osteosarcoma (OS), a highly aggressive primary bone tumor, belongs to the most common solid tumors in growing children. Since specific molecular targets for OS treatment remain to be identified, surgical resection combined with multimodal (neo-)adjuvant chemotherapy is still the only way to help res...

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Detalles Bibliográficos
Autores principales: Baldauf, Christina, Jeschke, Anke, Kanbach, Vincent, Catala-Lehnen, Philip, Baumhoer, Daniel, Gerull, Helwe, Buhs, Sophia, Amling, Michael, Nollau, Peter, Harroch, Sheila, Schinke, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567063/
https://www.ncbi.nlm.nih.gov/pubmed/26360410
http://dx.doi.org/10.1371/journal.pone.0137745