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CRISPR/Cas9 System as an Agent for Eliminating Polyomavirus JC Infection

Progressive multifocal leukoencephalopathy (PML) is a fatal demyelinating disease of the central nervous system (CNS) caused by reactivation of the human polyomavirus JCV gene expression and its replication in oligodendrocytes, the myelin producing cells in the brain. Once a rare disease seen in pat...

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Detalles Bibliográficos
Autores principales: Wollebo, Hassen S., Bellizzi, Anna, Kaminski, Rafal, Hu, Wenhui, White, Martyn K., Khalili, Kamel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567079/
https://www.ncbi.nlm.nih.gov/pubmed/26360417
http://dx.doi.org/10.1371/journal.pone.0136046