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CRISPR/Cas9 System as an Agent for Eliminating Polyomavirus JC Infection
Progressive multifocal leukoencephalopathy (PML) is a fatal demyelinating disease of the central nervous system (CNS) caused by reactivation of the human polyomavirus JCV gene expression and its replication in oligodendrocytes, the myelin producing cells in the brain. Once a rare disease seen in pat...
Autores principales: | Wollebo, Hassen S., Bellizzi, Anna, Kaminski, Rafal, Hu, Wenhui, White, Martyn K., Khalili, Kamel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567079/ https://www.ncbi.nlm.nih.gov/pubmed/26360417 http://dx.doi.org/10.1371/journal.pone.0136046 |
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