Autophagy Protects from Trastuzumab-Induced Cytotoxicity in HER2 Overexpressing Breast Tumor Spheroids

Multicellular tumor spheroids represent a 3D in vitro model that mimics solid tumor essential properties including assembly and development of extracellular matrix and nutrient, oxygen and proliferation gradients. In the present study, we analyze the impact of 3D spatial organization of HER2-overexp...

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Detalles Bibliográficos
Autores principales: Rodríguez, Cristina E., Reidel, Sara I., Bal de Kier Joffé, Elisa D., Jasnis, Maria A., Fiszman, Gabriel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567133/
https://www.ncbi.nlm.nih.gov/pubmed/26360292
http://dx.doi.org/10.1371/journal.pone.0137920

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567133/
https://www.ncbi.nlm.nih.gov/pubmed/26360292
http://dx.doi.org/10.1371/journal.pone.0137920

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