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Discovery of Drug Synergies in Gastric Cancer Cells Predicted by Logical Modeling
Discovery of efficient anti-cancer drug combinations is a major challenge, since experimental testing of all possible combinations is clearly impossible. Recent efforts to computationally predict drug combination responses retain this experimental search space, as model definitions typically rely on...
Autores principales: | Flobak, Åsmund, Baudot, Anaïs, Remy, Elisabeth, Thommesen, Liv, Thieffry, Denis, Kuiper, Martin, Lægreid, Astrid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567168/ https://www.ncbi.nlm.nih.gov/pubmed/26317215 http://dx.doi.org/10.1371/journal.pcbi.1004426 |
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