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A Prospective Study Evaluating Metabolic Capacity of Thiopurine and Associated Adverse Reactions in Japanese Patients with Inflammatory Bowel Disease (IBD)

Azathioprine (AZA) is frequently used in patients with inflammatory bowel disease (IBD). However, toxic adverse reactions frequently develop and limit the clinical benefits. Currently, the precise mechanisms underlying thiopurine-related toxicity are not well understood. To investigate the relations...

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Detalles Bibliográficos
Autores principales: Odahara, Shunichi, Uchiyama, Kan, Kubota, Takahiro, Ito, Zensho, Takami, Shinichiro, Kobayashi, Hiroko, Saito, Keisuke, Koido, Shigeo, Ohkusa, Toshifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567281/
https://www.ncbi.nlm.nih.gov/pubmed/26360046
http://dx.doi.org/10.1371/journal.pone.0137798