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A Prospective Study Evaluating Metabolic Capacity of Thiopurine and Associated Adverse Reactions in Japanese Patients with Inflammatory Bowel Disease (IBD)
Azathioprine (AZA) is frequently used in patients with inflammatory bowel disease (IBD). However, toxic adverse reactions frequently develop and limit the clinical benefits. Currently, the precise mechanisms underlying thiopurine-related toxicity are not well understood. To investigate the relations...
Autores principales: | Odahara, Shunichi, Uchiyama, Kan, Kubota, Takahiro, Ito, Zensho, Takami, Shinichiro, Kobayashi, Hiroko, Saito, Keisuke, Koido, Shigeo, Ohkusa, Toshifumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567281/ https://www.ncbi.nlm.nih.gov/pubmed/26360046 http://dx.doi.org/10.1371/journal.pone.0137798 |
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