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Assessment of Novel Anti-thrombotic Fusion Proteins for Inhibition of Stenosis in a Porcine Model of Arteriovenous Graft

BACKGROUND: Hemodialysis arteriovenous synthetic grafts (AVG) provide high volumetric blood flow rates shortly after surgical placement. However, stenosis often develops at the vein-graft anastomosis contributing to thrombosis and early graft failure. Two novel fusion proteins, ANV-6L15 and TAP-ANV,...

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Detalles Bibliográficos
Autores principales: Terry, Christi M., Zhuplatov, Ilya, He, Yuxia, Wun, Tze-Chein, Kim, Seong-Eun, Cheung, Alfred K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567316/
https://www.ncbi.nlm.nih.gov/pubmed/26360605
http://dx.doi.org/10.1371/journal.pone.0137381