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Anti-Inflammatory Effects of IL-27 in Zymosan-Induced Peritonitis: Inhibition of Neutrophil Recruitment Partially Explained by Impaired Mobilization from Bone Marrow and Reduced Chemokine Levels

Rapid activation of the innate immune system is critical for an efficient host response to invading pathogens. However, the inflammatory reaction has to be strictly controlled to minimize harmful immunopathology. A number of mediators including the cytokine interleukin-27 (IL-27) appear to be respon...

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Detalles Bibliográficos
Autores principales: Watzlawick, Ralf, Kenngott, Elisabeth E., Liu, Francesca Diane M., Schwab, Jan M., Hamann, Alf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567321/
https://www.ncbi.nlm.nih.gov/pubmed/26360023
http://dx.doi.org/10.1371/journal.pone.0137651