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High Throughput Sequencing Identifies MicroRNAs Mediating α-Synuclein Toxicity by Targeting Neuroactive-Ligand Receptor Interaction Pathway in Early Stage of Drosophila Parkinson's Disease Model
Parkinson’s disease (PD) is a prevalent neurodegenerative disorder with pathological features including death of dopaminergic neurons in the substantia nigra and intraneuronal accumulations of Lewy bodies. As the main component of Lewy bodies, α-synuclein is implicated in PD pathogenesis by aggregat...
Autores principales: | Kong, Yan, Liang, Xijun, Liu, Lin, Zhang, Dongdong, Wan, Chao, Gan, Zhenji, Yuan, Liudi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567341/ https://www.ncbi.nlm.nih.gov/pubmed/26361355 http://dx.doi.org/10.1371/journal.pone.0137432 |
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