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Partial Support Ventilation and Mitochondrial-Targeted Antioxidants Protect against Ventilator-Induced Decreases in Diaphragm Muscle Protein Synthesis

Mechanical ventilation (MV) is a life-saving intervention in patients in respiratory failure. Unfortunately, prolonged MV results in the rapid development of diaphragm atrophy and weakness. MV-induced diaphragmatic weakness is significant because inspiratory muscle dysfunction is a risk factor for p...

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Detalles Bibliográficos
Autores principales: Hudson, Matthew B., Smuder, Ashley J., Nelson, W. Bradley, Wiggs, Michael P., Shimkus, Kevin L., Fluckey, James D., Szeto, Hazel H., Powers, Scott K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567376/
https://www.ncbi.nlm.nih.gov/pubmed/26361212
http://dx.doi.org/10.1371/journal.pone.0137693